Pediatric Metastatic Odontogenic Ghost Cell Carcinoma: A Multimodal Treatment Approach
نویسندگان
چکیده
منابع مشابه
Pediatric Metastatic Odontogenic Ghost Cell Carcinoma: A Multimodal Treatment Approach
Odontogenic ghost cell carcinoma (OGCC) is a rare and aggressive tumor wherein optimal treatment remains uncertain. We report the first pediatric metastatic OGCC case treated with multimodal therapy: surgery, adjuvant chemoradiation, and adjuvant immunotherapy. Adjuvant therapy was utilized due to locally advanced disease with pathologic features indicative of high recurrence risk. This multimo...
متن کامل(P090) pediatric metastatic odontogenic ghost cell carcinoma: a multimodal treatment approach.
April 30, 2015 | ARS 2015 [1] OGCC can exhibit aggressive progression, warranting investigation into multimodal therapy. Given that adjuvant chemoradiation and immunotherapy are associated with improved outcomes in primary head and neck cancer, a similar application in OGCC may help guide optimal treatment. This approach was well tolerated in our pediatric patient, and he remains disease-free a...
متن کاملMetastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
Ghost cell odontogenic carcinoma (GCOC) is an exceedingly rare malignant tumor on the spectrum of already uncommon odontogenic or dentinogenic tumors. We describe here the case of metastatic GCOC in a patient with a history of recurrent dentinogenic ghost cell tumor of the mandible, now presenting with bilateral pleural effusions. We will discuss typical histopathologic and histochemical featur...
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Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in...
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Background: Transitional cell carcinoma (TCC) is a rare type of ovarian epithelial cancer. This type of ovarian cancer accounts for only 1% of superficial epithelial carcinomas. Ovarian cancer is a major clinical challenge in obstetrics and gynecology. The reason of this is the lack of specific symptoms for ovarian cancer before the recurrence and progression of the tumor, so many cases are not...
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ژورنال
عنوان ژورنال: Rare Tumors
سال: 2015
ISSN: 2036-3613,2036-3613
DOI: 10.4081/rt.2015.5855